CHENGSHENGTANG

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#### Products

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#### 5% Albendazole Oral Solution

For Veterinary Use Only
Composition:
Each ml. contains
Albendazole 50mg
Xanthan gum, Purified Water.
Description:
An off-white suspension.
Pharmacological properties:
A broad spectrum multi-purpose anthelmintic for the control of mature and developing immature forms of gastrointestinal rounds, lungworms, tapeworms, and adult liver fluke in cattle, sheep, and goats. The product is also ovicidal against fluke and roundworm eggs.
Benzimidazoles bind to nematode tubulin, a protein necessary for the formation and viability of microtubules. This occurs primarily in absorptive intestinal cells resulting in the absence of microtubules in the intestinal cells of the nematode, with the result that these cells cannot absorb nutrients, thus causing a consequent reduction in glycogen and effective starvation of the parasites. Structural differences have been shown to exist between tubulin from mammalian and helminth sources, resulting in the preferential toxicity of albendazole to the helminti and not to the host. Benzimidazoles have also been shown to inhitit the fumarate reductase system of helminths and impair energy production.
Target species:
Cattle, Sheep, and Goats
Indication:
Cattle: For removal and control of the following internal parasites: adult liver flukes (Fasciola hepatica); heads and segments of tapeworms (Moniezia benedeni, M. expansa); adult and 4th stage larvae of stomach worms (brown stomach worms including 4th stage inhibited larvae (Ostertagia ostertagi); barberpole worm (Haemonchus contortus, H. placei); small tomach worm (Trichostrongylus axei); adult and 4th stages larvae of intestinal worms (thread-necked intestinal worm (Nematodirus spathiger, N. helvetianus); small intestinal worm (Cooperia punctata and C. oncophora); adult stages of intestinal worms (hookworm (Bunostomum phlebotomum); bankrupt worm (Trichostrongylus colubriformis), nodular worm (Oesophagostomum radiatum); adult and 4th stage larvae of lungworms (Dictycaulus viviparus).
Sheep and goats: For removal and control of the following internal parasites: Adult liver flukes (Fasciola hepatica, Fascioloides magna); heads and segments of common tapeworms (Moniezia expansa) and fringed tapeworm (Thysanosoma actinoides); adult and fourth stage larvae of stomach worms (brown stomach worm (Ostetagia circumcincta and Marshallagia marshalli), barberpole worm (Haemonchus contortus), small stomach worm (Trichostrongylus axei); adult and fourth stage larvae of intestinal worms (thread-necked intestinal worm (Nematodirus spathiger and N. filicollis) , Cooper's worm (Cooperia oncophora), bankrupt worm (Trichostrongylus colubriformis), nodular worm (Oesophagostomum columbianum), and large-mouth bowel worm (Chabertia ovina); adult and larval stages of lungworms (Dictyocaulus filaria).
Administration and Dosage:
Oral administration.
Cattle: 10mg/kg body weight (2ml/10kg body weight).
Sheep and goats: 7.5mg/kg body weight (1.5ml/10kg body weight)
Contraindications:
Do not use in cases of known hypersensitivity to the active substance or to any of the other constituents
Do not use in female cattle during first 45 days of pregnancy or for 45 days after removal of bulls.
Do not use in ewes during first 30 days of pregnancy or for 30 days after removal of rams.
Do not use in does during first 30 days of pregnancy or for 30 days after removal of bucks.
Special warnings and precautions for each target species:
Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:
Too frequent and repeated use of anthelmintics from the same class, over an extended period of time
Underdosing, which may be due to underestimation of body weight, or misadministration of the product,
Special precautions for use in animals:
Do not use in other species
Special precautions to be taken by the person administering the medicinal product to animals:
Do not smoke or eat while handling the product and wash hands after use.
Contact with eyes should be avoided.
Keep out of the reach of children.
Drug interaction:
No drug interaction are reported in animals.
Withdrawal periods:
Meat
Cattle: 27 days
Sheep and goats: 7 days
Milk
Do not use in lactating dairy cattle
Do not use in lactating ewes and does.
Packing:
500ml/1000ml per bottle, 20 bottles/carton.
Shelf life: 36 months
Shelf life after opening: 15 days
Storage: In a cool and dry place under 30oC. Protected from light.

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Hebei Chengshengtang Animal Pharmaceutical Co., Ltd
Address: No. 25 Huangguan Road, Xinzhaidian Industrial Zone